Description
Baricitinib (Rheumatoid
Arthritis) - Forecast and Market Analysis to 2023
Summary
Rheumatoid arthritis (RA) is a
chronic autoimmune disease which causes inflammation and deformity of
the joints . It affects over seven million individuals in the 10MM
covered in this report (US, France, Germany, Italy, Spain, UK, Japan,
Australia, China, and India) and the prevalence is expected to grow
to just over 8.5 million individuals by 2023. The anti-TNFs have been
effective in treating the signs and symptoms of RA and inhibiting
progression to erosive bone disease. However, the landscape is
quickly changing with the introduction of biosimilars, novel
biologics, and a class of oral therapies known as JAK inhibitors, all
of which will change the market dynamics between 2013 and 2023. With
the anti-TNFs as extremely effective therapies for RA, the market is
extremely competitive for new entrants and will undergo further
pressure as biosimilars are approved and launch.
Eli Lilly and Incyte are
jointly developing baricitinib, an oral JAK inhibitor, for the
treatment of patients with moderate to severe RA. Baricitinib has
roughly equal affinity for JAK1 and JAK2, preventing the
intracellular signaling cascades that lead to the production of IL-6
and IL-23, thereby reducing inflammation.
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Scope
- Overview of Rheumatoid
Arthritis, including epidemiology, etiology, symptoms, diagnosis,
pathology and treatment guidelines as well as an overview on the
competitive landscape.
- Detailed information on
Baricitinib including product description, safety and efficacy
profiles as well as a SWOT analysis.
- Sales forecast for
Baricitinib for the top 10 countries from 2013 to 2023.
- Sales information covered
for the US, France, Germany, Italy, Spain, the UK, Japan, Australia,
China and India.
Reasons
to buy
- Understand and capitalize by
identifying products that are most likely to ensure a robust return.
- Stay ahead of the
competition by understanding the changing competitive landscape for
Rheumatoid Arthritis.
- Effectively plan your M&A
and partnership strategies by identifying drugs with the most
promising sales potential.
- Make more informed business
decisions from insightful and in-depth analysis of Baricitinib
performance.
- Obtain sales forecast for
Baricitinib from 2013-2023 in top 10 countries (the US, France,
Germany, Italy, Spain, the UK and Japan, Australia, China and India).
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Detail Report With Complete TOC at
Table
of Content
1 Table of Contents
1 Table of Contents 5
1.1 List of Tables 8
1.2 List of Figures 9
2 Introduction 10
2.1 Catalyst 10
2.2 Related Reports 11
2.3 Upcoming Related Reports
14
3 Disease Overview 15
3.1 Etiology and
Pathophysiology 15
3.1.1 Etiology 15
3.1.2 Pathophysiology 15
3.2 Symptoms 19
3.3 Prognosis 20
3.4 Quality of Life 20
4 Disease Management 21
4.1 Diagnosis and Treatment
Overview 21
4.1.1 Diagnosis 21
4.1.2 Treatment Guidelines 23
4.1.3 Leading Prescribed Drugs
for the Treatment of RA 33
4.1.4 Clinical Practice 34
5 Competitive Assessment 39
5.1 Overview 39
6 Unmet Need and Opportunity
41
6.1 Overview 41
6.2 Development of
Cost-Effective Therapies 42
6.2.1 Unmet Need 42
6.2.2 Gap Analysis 43
6.2.3 Opportunity 43
6.3 Biomarkers to Predict
Responsiveness to Therapy 44
6.3.1 Unmet Need 44
6.3.2 Gap Analysis 46
7 Pipeline Assessment 53
7.1 Overview 53
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