"The
Report OpportunityAnalyzer: Small Cell Lung Cancer (SCLC) -
Opportunity Analysis and Forecasts to 2024 provides information on
pricing, market analysis, shares, forecast, and company profiles for
key industry participants. - MarketResearchReports.biz"
Initially
considered a curable disease due to substantial sensitivity to
first-line chemotherapies, Small
Cell Lung Cancer (SCLC)
remains a fatal disease with poor outcomes due to high relapse rates,
with the majority of patients surviving one year or less after
diagnosis. Unlike non-small cell lung cancer (NSCLC), in which major
advances in treatment have been made following the approval of
several targeted therapies, the field of SCLC has seen little
advancement for several decades.
For
the purposes of this report, GlobalData considers the Global SCLC
market to include SCLC-specific drug sales in the 7MM (US, 5EU
[France, Germany Italy, Spain, and the UK], and Japan). The current
market across these countries is dominated by the sale of major
generic chemotherapy regimens. GlobalData estimated that the Global
SCLC market was valued at $198m in 2014. Following the expected
approval of new agents over the forecast period, relapsed/refractory
patients will have significantly improved therapeutic options leading
to rapid uptake of these drugs. The increased use of branded
therapies in treatment-nave and advanced patients, such as Yervoy,
Opdivo, roniciclib, and sacituzumab govitecan, will be the primary
driver of the substantial growth in the SCLC market over the forecast
period, which is expected to grow at a positive CAGR of almost 28% in
the 7MM.
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Highlights
Key Questions Answered
- Based on interviews with key opinion leaders (KOLs), GlobalData has identified the major unmet needs in the SCLC marketplace. Will the leading pipeline agents fulfil these unmet needs during the forecast period (2014-2024)?
- What research and development (R&D) strategies will companies leverage to compete in the future SCLC marketplace?
- Which pipeline products are poised to make a major clinical and commercial impact?
- What clinical and commercial factors are likely to influence SCLC drug uptake in the 7MM?
Key Findings
- The greatest driver of growth within the Global SCLC market will be the launch and increased use of premium-priced therapies, including anti-PD-1 immunotherapy and targeted agents such as roniciclib and sacituzumab govitecan. GlobalData expects Yervoy to reach blockbuster status by the end of the forecast period, with global sales of around $1bn.
- Continuous dosing regimens until disease progression and adoption of maintenance setting following induction therapy for first-line patients will contribute to the increased sales of branded drugs.
- Toxicity is likely to remain a major concern as new first-line treatment options are approved considering companies are developing them in combination with platinum-etoposide. Therefore, substantial opportunity remains to develop therapies that have improved safety profiles compared with agents in the current SCLC pipeline.
- An increasing emphasis on cost-consciousness is anticipated over the forecast period, which will limit premium pricing opportunities for developers of SCLC pipeline agents. GlobalData expects this era of austerity and healthcare reform to make it increasingly more difficult for pharmaceutical companies to gain reimbursement approval for their new SCLC therapies.
Scope
- Overview of SCLC, including epidemiology, etiology, pathophysiology, symptoms, diagnosis, and current treatment options.
- Topline SCLC drug market revenue from 2014-2024, annual cost of therapy (ACOT), and major product sales in six patient segments during the forecast period are included.
- Key topics covered include strategic competitor assessment, market characterization, unmet needs, opportunities, R&D strategies, and clinical trial mapping for the SCLC market.
- Pipeline analysis: comprehensive data split across different phases, emerging novel trends under development, synopses of innovative early-stage projects, and detailed analysis of late-stage pipeline products. An interactive clinical and commercial analyzer tool is available.
- Analysis of the current and future market competition in the global SCLC market. Insightful review of the key industry drivers, restraints, and challenges. Each trend is independently researched to provide qualitative analysis of its implications.
Reasons to buy
The report will enable you
to -
- Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
- Develop business strategies by understanding the trends shaping and driving the global SCLC therapeutics market.
- Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the SCLC market in the future.
- Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
- Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
- Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.
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Table Of Content
1
Table of Contents 9
1.1
List of Tables 13
1.2
List of Figures 17
2
Introduction 19
2.1
Catalyst 19
2.2
Related Reports 19
2.3
Upcoming Related Reports 20
3
Disease Overview 21
3.1
Etiology and Pathophysiology 21
3.1.1
Etiology 21
3.1.2
Pathophysiology 22
3.2
Symptoms 23
3.3
Diagnosis 24
3.4
Clinical Staging 26
3.5
Prognostic Factors 29
3.6
Quality of Life 29
4
Epidemiology 31
4.1
Disease Background 31
4.2
Risk Factors and Comorbidities 32
4.3
Global Trends 34
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