Research Report on “
EpiCast
Report: Duchenne Muscular Dystrophy - Epidemiology
Forecast to 2023 ”
Duchenne muscular dystrophy
(DMD) and Becker muscular dystrophy (BMD) are rare progressive muscle
wasting disorders.
GlobalData epidemiologists
forecast that the diagnosed prevalent cases of DMD (all ages) in the
6MM will increase from 17,675 diagnosed prevalent cases in 2013 to
17,712 diagnosed prevalent cases in 2023, at an Annual Growth Rate
(AGR) of 0.02%. The 6MM had an estimated 6,076 diagnosed prevalent
cases of DMD for ages 5-13 years in 2013, and the number of diagnosed
prevalent cases is expected to increase to 6,250 by 2023, at an AGR
of 0.29%. GlobalData epidemiologists forecast that the diagnosed
prevalent cases of DMD with nonsense mutations (all ages) in the 6MM
will increase from 2,260 diagnosed prevalent cases in 2013 to 2,264
diagnosed prevalent cases in 2023, at an AGR of 0.02%.
GlobalData epidemiologists
used the best available data from peer-reviewed journal articles and
national DMD mutation databases to arrive at a meaningful and
in-depth analysis of the diagnosed prevalent cases of DMD and BMD for
men in the 6MM based on: a confirmed deletion, duplication, or point
mutation in the DMD gene; reduced or absent dystrophin
immunolabeling; or cases fulfilling “definite” or “probable”
criteria of the Muscular Dystrophy Surveillance Tracking and Research
Network (MD STARnet). For all the 6MM, the diagnosed prevalent cases
of DMD and BMD were segmented by age, which facilitates an
understanding of the distribution of the disease within the
population, and informs strategies to improve the management of the
disease. The diagnosed prevalent cases of DMD in each of the 6MM were
further segmented by therapeutically significant populations
including the applicability of exon skipping therapies (exons 51, 45,
53, and 44), nonsense mutations, and cases ages 5-13 years in these
markets.
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Scope
- The Duchenne Muscular Dystrophy (DMD) EpiCast Report provides an overview of the risk factors, comorbidities, and the global and historical trends for DMD in the six major markets (6MM) (US, France, Germany, Italy, Spain, and UK). It includes a 10-year epidemiological forecast for the diagnosed prevalent cases of DMD and Becker Muscular Dystrophy (BMD) in men, segmented by age (in 10-year age groups beginning at 0 years and ending at =40 years for cases of DMD with a special focus on the subgroup of ages 5-13 years, and in 15-year age groups beginning at 0 years and ending at =75 years for cases of BMD) in these markets. Additionally, the diagnosed prevalent cases of DMD (all ages) are further segmented by the applicability of exon skipping therapies (exons 51, 45, 53, and 44) and nonsense mutations.
- The DMD epidemiology report is written and developed by Mastersand PhD-level epidemiologists.
- The EpiCast Report is in-depth, high quality, transparent and market-driven, providing expert analysis of disease trends in the 6MM.
Reasons to buy
- Develop business strategies by understanding the trends shaping and driving the global DMD market.
- Quantify patient populations in the global DMD market to improve product design, pricing, and launch plans.
- Organize sales and marketing efforts by identifying the sex and age groups that present the best opportunities for DMD therapeutics in each of the markets covered.
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Table
of Content :
1 Table of Contents
1 Table of Contents 6
1.1 List of Tables 8
1.2 List of Figures 9
2 Introduction 10
2.1 Catalyst 10
2.2 Related Reports 11
2.3 Upcoming Related Reports
11
3 Epidemiology 12
3.1 Disease Background 12
3.2 Risk Factors and
Comorbidities 13
3.3 Global Trends 14
3.4 Forecast Methodology 16
3.4.1 Sources Used 21
3.4.2 Sources Not Used 23
3.4.3 Forecast Assumptions and
Methods 24
3.5 Epidemiological Forecast
for DMD (2013-2023) 29
3.5.1 Diagnosed Prevalent
Cases of DMD (All Ages) 29
3.5.2 Diagnosed Prevalent
Cases of DMD (Ages 5-13 Years) 31
3.5.3 Age-Specific Diagnosed
Prevalent Cases of DMD (All Ages) 32
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